An electrogenetic interface to program mammalian gene expression by direct current - Nature Metabolism
www.nature.com
Huang et al. develop an interface to allow electrode-mediated stimulation of gene expression in human cells, utilizing direct current-generated reactive oxygen species to stimulate transgene expression downstream of the KEAP1–NRF2 biosensor. In a type 1 diabetic mouse model, this interface is demonstrated to ameliorate hyperglycemia by stimulating insulin expression.
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The original was posted on /r/science by /u/chrisdh79 on 2023-08-01 01:28:37.

Original Title: Scientists Control Human DNA with Electricity in ‘Leap Forward’, Study Reports | Breakthrough research represents “the missing link that will enable wearables to control genes in the not-so-distant future.”