APOE4 gene may influence brain barrier function in early stages of Alzheimer’s disease
www.psypost.org
APOE4 carriers had higher blood-brain barrier permeability, even without cognitive decline or amyloid beta buildup, suggesting early vascular changes that may be linked to Alzheimer’s risk and neurodegeneration.
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The original was posted on /r/science by /u/chrisdh79 on 2024-11-26 11:01:13+00:00.

Original Title: APOE4 gene may influence brain barrier function in early stages of Alzheimer’s disease | The study found increased permeability in the blood-brain barrier of APOE4 carriers, including those without cognitive symptoms or amyloid beta buildup.