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The original was posted on /r/cfs by /u/Hip_III on 2024-08-06 23:54:57+00:00.

Molnupiravir is an antiviral that works for RNA viruses such as coxsackievirus B, echovirus and COVID, which are viruses linked to ME/CFS.

One patient with moderate ME/CFS went into remission after a 5-day course of molnupiravir (which she took for an acute COVID infection). She remained in remission for several weeks after the molnupiravir, but unfortunately her ME/CFS symptoms gradually returned.

However, if 5 days of molnupiravir puts a patient into remission even for a few weeks, it is possible that repeat courses of molnupiravir could be used to maintain remission.

A 5-day course of generic molnupiravir (normally taken at 800 mg twice daily) can cost as little as $50.

There were some concerns with possible carcinogenicity effects from molnupiravir, but a study which gave this antiviral to mice continuously for 6 months observed no carcinogenic effects. And another study which used the Ames test for genotoxicity found no genotoxic effects.

I also know of another ME/CFS patient who took molnupiravir 800 mg twice daily for 5 days, and moved from moderate to mild ME/CFS as a result.

Has anyone else taken molnupiravir, and found benefits for their ME/CFS?