CB1 Receptor Antagonist Selonabant (ANEB-001) Blocks Acute THC Effects in Healthy Volunteers: A Phase II Randomized Controlled Trial - PubMed
pubmed.ncbi.nlm.nih.gov
Emergency department visits due to cannabinoid-induced toxicity, including acute cannabinoid intoxication (ACI) have increased worldwide as more states have liberalized cannabis policy. ACI symptoms include anxiety, panic attacks, tachycardia, and psychosis, primarily mediated through cannabinoid ty …
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The original was posted on /r/science by /u/OregonTripleBeam on 2025-05-12 17:12:18+00:00.

Original Title: A randomized, double-blind, placebo-controlled study determined that CB1 receptor antagonist selonabant was effective at blocking THC-induced effects in healthy adults, finding that selonabant significantly reduced “feeling high” and increased “alertness” in subjects compared to a placebo.