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The original was posted on /r/science by /u/zOxydrOp on 2025-08-13 16:15:47+00:00.

Original Title: A recent study shows that circadian rhythm disruptions play a key role in the progression of the rare neurodegenerative disorder Machado-Joseph disease (MJD). As MJD advances, the body’s internal clock loses robustness, causing e.g. irregular sleep-wake cycles and impaired temperature regulation