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The original was posted on /r/science by /u/CUAnschutzMed on 2025-09-25 15:17:26+00:00.

Original Title: A groundbreaking study reveals that rheumatoid arthritis doesn’t begin when symptoms appear. Instead, it starts silently, years earlier. The study offers the most detailed view yet of how RA develops, mapping immune changes in people at long risk before joint pain begins.