Powerful new oral painkiller blocks signals without sedation or addiction
newatlas.com
Scientists have shown the efficacy of a new non-opioid oral painkiller known as ADRIANA, the world's first selective α2B-adrenoceptor antagonist – a receptor subtype not previously targeted for analgesics. In clinical trials so far, it has provided powerful pain relief without sedation or risk of…
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The original was posted on /r/upliftingnews by /u/sg_plumber on 2025-10-08 17:42:15+00:00.

Original Title: Powerful new non-opioid oral painkiller blocks signals without sedation or addiction: Kyoto University’s ‘ADRIANA’ targets the α2B adrenoceptor, a little-studied brain receptor that plays a major role in mechanical pain. It could revolutionize post-operative care and chronic pain relief